Treating Lichen Sclerosus with Antibiotics

| June 8, 2012 | 0 Comments More

I ran across a couple of publications about using antibiotics for treating Lichen Sclerosus. While most doctors prescribe topical steroids, particularly clobetasol propionate for treating Lichen Sclerosus, there is apparently some evidence suggesting that Lyme Disease or Mycoplasma infections can trigger LS (as well as other autoimmune diseases). These would commonly be treated with long term antibiotic therapy. There was a study on the effect of penicillin and cephalosporin therapy on patients with lichen sclerosus who had responded poorly to treatment with potent topical corticosteroids. “Fifteen patients with lichen sclerosus were treated for 3-21 months with either penicillin or cephalosporins in an observational study. Thirteen patients (nine women, four men) received penicillin, including intramuscular penicillin G benzathine suspension and/or oral penicillin V potassium, amoxicillin, or amoxicillin/clavulanate potassium. Two additional men received cephalosporins, either intramuscular ceftriaxone sodium or oral cefadroxil monohydrate. All patients showed a significant response, evident within a few weeks. Most striking was the rapid relief of pain, pruritus and burning. Four patients cleared completely, four experienced marked improvement, and the remaining seven had a favorable improvement of symptoms with incomplete clearing of lesions.”

More on the study:

If you have been exposed to Lyme disease in the past, or have had a tick bite, it might be worth while to check with your doctor about getting tested for Lyme and Mycoplasma. 75% of Lyme patients also tested positive for mycoplasma so it is common to have both. Commonly a doctor would  administer a CD57 blood test for Lyme’s and a Mycoplasma antibody test. Apparently eradicating mycoplasma is a lengthy procedure with antibiotics – it can take 5-6 months, and can reoccur years later. But if you do test positive, it could be the reason why Lichen was triggered, and treating the underlying infection can possibly help clear the Lichen as well. I have seen comments from women who have had success with this approach, so if nothing else is working for you, this could be worth looking into with your doctor. Long term consumption of antibiotics will also destroy beneficial bacteria in the gut, as well as increase the likelihood of yeast infections, so make sure to up your pro-biotic supplement intake to compensate.

Dr. Nicholson is a leading expert on the Lyme/Mycoplasma link to autoimmune diseases, more information on his insights can be found in this article:


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Category: Lichen Sclerosus (LS)

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